Thesis environment

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Thesis environment

I obtained counts of ER visits attributed to a mental health disorder, suicide or self-inflicted injury, and homicide or injury purposely inflicted by others in the state of California between and As global temperatures continue to rise and heat waves are predicted to become more frequent, it is important to understand how mental health outcomes may be impacted.

Thyroid cancer incidence has also been increasing over a similar time frame; ionizing radiation is an established risk factor.

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The carcinogenicity of exposure to non-ionizing radiation from cell phone use is a controversial topic and previous studies have reached inconsistent conclusions, such as with respect to brain cancer. However, no study has directly investigated the association between cell phone use and thyroid cancer.

A population-based case-control study was conducted in Connecticut between andwhich recruited histologically confirmed thyroid cancer cases Thesis environment population-based controls.

Several metrics capturing frequency and duration of self-reported cell phone use patterns were constructed, including phone use hours per day, number of phone calls per day, and phone use years.

Thesis environment

Multivariate unconditional logistic regression models were used to estimate the associations between cell phone use and risk thyroid cancer. Cell phone use was not associated with the risk of thyroid cancer OR: However, a suggestive trend of increased risk of thyroid cancer microcarcinoma was observed for long-term and frequent users.

Future large prospective studies are warranted to further investigate the association. Understanding the Role of Effect Modification of Maternal Risk Factors on Infant Respiratory Distress Outcomes We sought to determine which maternal covariates are most associated with infant respiratory distress outcomes.

Similarly, this research analyzes which covariates best predict or determine the total length of time an infant with respiratory distress syndrome requires.

However, there are limited studies directly focusing on the ambient air quality impact by this industry. We conducted a community-based, cross-section study in Belmont county, Ohio to assess the association between the detection of indoor and outdoor VOCs benzene, ethylbenzene and toluene and the residential proximity to the unconventional natural gas wells.

There are totally 66 participants involved in our study. The Pace Analytical Services Company analyzed the concentration of benzene, ethylbenzene and toluene in both indoor and outdoor samples to calculate the time weighted average concentration.

Then we calculated the inverse distance weighted IDW matrix for 2 km and 5 km.

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We performed chi-square test and Wilcoxon rank-sum test and univariable logistic regression analysis to assess whether the VOCs were more likely to be detected for the participants living within 2km from the nearest wells compared to the participants living out of 2 km from the nearest wells.

The detection rate of indoor VOCs are much high than the outdoor detection rate, which were too low to be considered. Also the detection rate of indoor VOCs among houses within 2 km to the wells are higher comparing to the houses out of 2 km from the wells.

Observed both indoor and outdoor toluene and ethylbenzene concentration were below the Reference concentration RfC by the U. These analyses require more refined inverse-distance weighted proximity matrix and longer sampling duration for air samples.

Our findings in this pilot study did provide some insights and data base for further investigation in Ohio unconventional natural gas development and air quality impacts. In particular, it has been hypothesized that prolonged exposure to crumb rubber may increase risk of cancer. The objective of this thesis was to evaluate the carcinogenicity potential of chemicals present in crumb rubber infill.

A systematic literature review was conducted to identify chemical constituents of crumb rubber infill. Specific thresholds were set for each of the four predictive models and the chemicals were prioritized in 15 categories based on the strength and consistency of the predictions.

A total of compounds linked to crumb rubber infill based on 20 published studies were identified. Of these, chemicals met the threshold criteria and thus were assigned a priority ranking. Eight chemicals were prioritized into the highest ranking: The results indicate that several components of crumb rubber contain chemicals with carcinogenic potential.

The priority rankings can inform the focus and design of future exposure and epidemiologic studies. Toxicology and Pharmacokinetics of Perfluoroorctanoic Acid PFOA The purpose of this thesis is to convert the environmental PFOA exposures to internal doses in a specific population and to extrapolate the internal dose into estimates of individual risk.

Because exposure to PFOA is suspected to cause a number of human health effects, in order to better understand the impact of environmental PFOA exposure, this thesis first reviewed major epidemiology studies on the most frequently reported cancer and non-cancer human health effects.

This thesis also demonstrates the utility of pharmacokinetic models and their dependency on the available parameters for model building. Perfluorooctanoic acid PFOAa widely used synthetic chemical, is a growing public health concern.

Detectable serum levels can be found in most residents of the U. The purpose of this thesis is to convert the environmental PFOA exposures to internal doses in a specific population and to extrapolate the internal dose into estimates of individual risk.

The thesis also compared one-compartment models using pharmacokinetic parameters from different human studies, and applied them to drinking water data from the State of Colorado.Field trips always provide extra food for thought where debates in the classroom come to life in the face of lived realities in the city.

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